Essential Thrombocythaemia and Peripheral Gangrene
نویسندگان
چکیده
منابع مشابه
Headache in essential thrombocythaemia
Headache is frequently reported as one of the neurological manifestations of essential thrombocythaemia (ET) and other myeloproliferative neoplasms. It is associated with considerable morbidity; yet, it is a frequently under-recognised symptom. In patients with ET, headaches may be attributable to the disease, to the prescribed ET treatment, or unrelated to ET. The majority of headaches in ET a...
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A 99-year-old woman was admitted following a mechanical fall. The patient suffered from frequent falls averaging around six falls per year. On this occasion the patient explained that she had simply lost her balance and denied any further symptoms. The patient’s past medical history was significant for essential thrombocythaemia diagnosed 10 years earlier which was initially managed with hydrox...
متن کاملEssential thrombocythaemia: challenges and evidence-based management.
Essential thrombocythaemia was first described over 70 years ago. This condition is dominated by thrombotic and haemorrhagic complications and, in the long-term, by risk of transformation to myelofibrosis and/or acute leukaemia. However, it is heterogeneous both clinically and biologically. Here, a review of current concepts in disease aetiology and management is offered with reference to recen...
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Mutations of MPL are present in a significant proportion of patients with the myeloproliferative neoplasms (MPN), primary myelofibrosis (PMF), and essential thrombocythaemia (ET). The most frequent of these mutations, W515L and W515K, occur in exon 10 of MPL, which encodes the receptor for thrombopoietin. Another exon 10 mutation, MPL S505N, has been shown to be a founder mutation in several pe...
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© 2014 The Authors. doi: 10.2340/00015555-1653 Journal Compilation © 2014 Acta Dermato-Venereologica. ISSN 0001-5555 Urticarial vasculitis is a form of leucocytoclastic vasculitis whereby the skin lesions resemble urticaria. It is associated with systemic lupus erythematosus, Sjögren’s syndrome, hepatitis B and C viruses (1). Rarely it is associated with an underlying haematological disorders a...
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ژورنال
عنوان ژورنال: BMJ
سال: 1974
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.3.5930.548